Suvarna Garge (Editor)

TRAF5

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Species
  
Human

Entrez
  
7188

Human
  
Mouse

Ensembl
  
ENSG00000082512

TRAF5

Aliases
  
TRAF5, MGC:39780, RNF84, TNF receptor associated factor 5

External IDs
  
MGI: 107548 HomoloGene: 27079 GeneCards: TRAF5

TNF receptor-associated factor 5 is a protein that in humans is encoded by the TRAF5 gene.

Contents

Function

The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. Alternate transcriptional splice variants have been characterized.

Interactions

TRAF5 has been shown to interact with:

References

TRAF5 Wikipedia
(Text) CC BY-SA


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