Entrez 10293 | Ensembl ENSG00000183763 | |
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External IDs MGI: 1096377 HomoloGene: 31343 GeneCards: TRAIP |
TRAF-interacting protein is a protein that in humans is encoded by the TRAIP gene.
This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis.
Interactions
TRAF interacting protein has been shown to interact with FLII, TRAF1 and TRAF2.
References
TRAF interacting protein Wikipedia(Text) CC BY-SA