Symbol TOX3 Entrez 27324 OMIM 611416 | Alt. symbols TNRC9, CAGF9 HUGO 11972 RefSeq XM_049037 | |
TOX high mobility group box family member 3, also known as TOX3, is a human gene.
The protein encoded by this gene is a member of a subfamily of transcription factors that also includes TOX, TOX2, and TOX4 that share almost identical HMG-box DNA-binding domains which function to modify chromatin structure.
Disease linkage
Mutations in the TOX3 gene are associated with an increased risk of breast cancer.
References
TOX3 Wikipedia(Text) CC BY-SA