Aliases TNIK Human Mouse Ensembl ENSG00000154310 | Species Human Entrez 23043 | |
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External IDs MGI: 1916264 HomoloGene: 77943 GeneCards: TNIK | ||
TRAF2 and NCK-interacting protein kinase is an enzyme that in humans is encoded by the TNIK gene.
Contents
Function
Germinal center kinases (GCKs), such as TNIK, are characterized by an N-terminal kinase domain and a C-terminal GCK domain that serves a regulatory function.
Interactions
TNIK has been shown to interact with KIAA0090, although the significance is unclear. TNIK has been shown to phosphorylate Gelsolin, a protein involved in F-actin depolymerisation thus inducing cytoskeletal changes.
References
TNIK Wikipedia(Text) CC BY-SA