Species Human Entrez 7073 | Human Mouse Ensembl ENSG00000151923 | |
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Aliases TIAL1, TCBP, TIAR, TIA1 cytotoxic granule-associated RNA binding protein-like 1 External IDs MGI: 107913 HomoloGene: 87796 GeneCards: TIAL1 | ||
Nucleolysin TIAR is a protein that in humans is encoded by the TIAL1 gene.
The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing.
References
TIAL1 Wikipedia(Text) CC BY-SA