Aliases TGIF2 Human Mouse Ensembl ENSG00000118707 | Species Human Entrez 60436 | |
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External IDs MGI: 1915299 HomoloGene: 32514 GeneCards: TGIF2 | ||
Homeobox protein TGIF2 is a protein that in humans is encoded by the TGIF2 gene.
The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor. The encoded protein appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and overexpressed in some ovarian cancers, and mutations in this gene can cause holoprosencephaly.
References
TGIF2 Wikipedia(Text) CC BY-SA