Species Human Entrez 7030 | Human Mouse Ensembl ENSG00000068323 | |
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Aliases TFE3, RCCP2, RCCX1, TFEA, bHLHe33, transcription factor binding to IGHM enhancer 3 External IDs MGI: 98511 HomoloGene: 4755 GeneCards: TFE3 | ||
Transcription factor E3 is a protein that in humans is encoded by the TFE3 gene.
Contents
Function
TFE3, a member of the helix-loop-helix family of transcription factors, binds to the mu-E3 motif of the immunoglobulin heavy-chain enhancer and is expressed in many cell types (Henthorn et al., 1991).[supplied by OMIM]
Interactions
TFE3 has been shown to interact with:
Translocations
A proportion of renal carcinomas (RCC) that occur in young patients are associated with translocations involving the TFE3 gene at chromosome Xp11.2 PRCC
References
TFE3 Wikipedia(Text) CC BY-SA