Samiksha Jaiswal (Editor)

TFE3

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
Species
  
Human

Entrez
  
7030

Human
  
Mouse

Ensembl
  
ENSG00000068323

TFE3

Aliases
  
TFE3, RCCP2, RCCX1, TFEA, bHLHe33, transcription factor binding to IGHM enhancer 3

External IDs
  
MGI: 98511 HomoloGene: 4755 GeneCards: TFE3

Transcription factor E3 is a protein that in humans is encoded by the TFE3 gene.

Contents

Function

TFE3, a member of the helix-loop-helix family of transcription factors, binds to the mu-E3 motif of the immunoglobulin heavy-chain enhancer and is expressed in many cell types (Henthorn et al., 1991).[supplied by OMIM]

Interactions

TFE3 has been shown to interact with:

  • E2F3,
  • Microphthalmia-associated transcription factor, and
  • Mothers against decapentaplegic homolog 3

    • Translocations

    A proportion of renal carcinomas (RCC) that occur in young patients are associated with translocations involving the TFE3 gene at chromosome Xp11.2 PRCC

    References

    TFE3 Wikipedia
    (Text) CC BY-SA


    Similar Topics