Species Human Entrez 6904 | Human Mouse Ensembl n/a | |
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Aliases TBCD, SSD-1, tfcD, tubulin folding cofactor D External IDs MGI: 1919686 HomoloGene: 4368 GeneCards: TBCD | ||
Tubulin-specific chaperone D is a protein that in humans is encoded by the TBCD gene.
Contents
Function
Cofactor D is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
Interactions
TBCD has been shown to interact with ARL2.
References
TBCD Wikipedia(Text) CC BY-SA