Aliases SNPH, bA314N13.5 Human Mouse Ensembl ENSG00000101298 | Species Human Entrez 9751 | |
External IDs MGI: 2139270 HomoloGene: 8817 GeneCards: SNPH | ||
Gene music using protein sequence of snph syntaphilin
Syntaphilin is a protein that in humans is encoded by the SNPH gene.
Contents
Function
Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. Alternative splicing results in multiple transcript variants encoding different isoforms.
References
Syntaphilin Wikipedia(Text) CC BY-SA