Dudley Sutphin (1875–1926), an American lawyer and tennis player
William H. Sutphin (1887–1970), an American politician
C.H. Sutphen, founder of Sutphen, an American emergency service vehicle manufacturing company
Beverly Sutphin, character in John Waters' 1994 film Serial Mom
Sutphin Boulevard, a street in Queens, New York City, with several rail stations of this name.
Sutphin (also spelled Sutphen) is a surname which occurs in the United States. It is an Americanized form of the Dutch surname Zutphen or van Zutphen, from the place-name Zutphen (used for residents), meaning "south fen".