Kingdom Bacteria Family Micrococcaceae Phylum Actinobacteria Order Actinomycetales | Class Actinobacteria Species S. mucilaginosus Rank Genus | |
Similar Rothia, Micrococcaceae, Rothia dentocariosa, Aerococcus, Gemella | ||
Stomatococcus mucilaginous(now known as Rothia mucilaginosa) is a Gram-positive, coagulase-negative, encapsulated, non-spore-forming and non-motile coccus, present in clusters, tetrads or pairs that is a part of the normal oropharyngeal flora. Belonging to the family Micrococcaceae, it was first isolated from the mucous membrane of the cheek and gingiva. It is an oral commensal, that has been linked to causing severe bacteremia in immunocompromised patients. This bacterium has also been shown to form biofilms, similar to that of Pseudomonas aeruginosa. S. mucilaginous is a cohabitant in the lower airways of patient with bronchiectasis
Contents
Morphology
Stomatococcus mucilaginous is a Gram-positive, coagulase-negative, encapsulated, non-spore-forming and non-motile coccus, present in clusters, tetrads or pairs. S. mucilaginous can easily be confused for the bacteria from the genera Micrococcus and Staphylococcus. One way that it can be distinguished from those two is by its strong adherence to the solid medium substrate that its colonies form. Another way is by its weak or absent catalase reaction, failure to grow on 5% NaCl media or its glucose and sucrose fermentation.
Pathology
Stomatococcus mucilaginous has been linked to Bronchiectasis, showing that an inhibition of the COX-2 inhibitor is largely related to an increased production of PGE2, which has been shown to be immunosuppressive in animal models of bacterial pneumonias and sepsis. The inhibition of COX-2 improved survival in mice, suggesting that the pathogenic effects of S. mucilaginous are related to the induction of COX-2 It is also closely associated with Bacteremia, sepsis, and endocarditis.
Antibiotics
Stomatococcus mucilaginous is resistant to the quinolone class of antibiotics, with extreme resistance to fluoroquinolones. Sensitivity, as of 2003, is still found in trimethoprim-sulfamethoxazole, vancomycin and bacitracin.