Kingdom Plantae Family Menispermaceae Higher classification Menispermaceae | Order Ranunculales Scientific name Stephania Rank Genus | |
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Similar Menispermaceae, Stephania tetrandra, Stephania japonica, Aristolochia fangchi, Cocculus | ||
Medicinal rice p5d formulations for stephania excess pankaj oudhia s medicinal plant database
Stephania is a genus of flowering plants in the family Menispermaceae, native to eastern and southern Asia and Australasia. They are herbaceous perennial vines growing to around four metres tall, with a large, woody caudex. The leaves are arranged spirally on the stem, and are peltate, with the leaf petiole attached near the centre of the leaf. The name Stephania comes from the Greek, "a crown". This refers to the anthers being arranged in a crown like manner.
Contents
- Medicinal rice p5d formulations for stephania excess pankaj oudhia s medicinal plant database
- Medicinal rice p5 formulations for stephania overdose pankaj oudhia s medicinal plant database
- Toxicity
- Chemistry
- Selected species
- References
One species, S. tetrandra, is among the 50 fundamental herbs used in traditional Chinese medicine, where it is called han fang ji (漢防己, "Chinese fang ji"). Other plants named fang ji are sometimes substituted for it. Other varieties substituted include Cocculus thunbergii, C. trulobus, Aristolochia fanchi, Stephania tetrandria, and Sinomenium acutun. Notable among these is guang fang ji (廣防己, "(GuangDong,GuangXi) fang ji", Aristolochia fanchi. Because of its toxicity, it is used in TCM only with great caution.
Medicinal rice p5 formulations for stephania overdose pankaj oudhia s medicinal plant database
Toxicity
There is evidence that a few species of Stephania are toxic. However, the most commonly available species in the United States, Stephania tetrandra, has not been shown to be toxic. Any confusion regarding the possible toxicity of Stephania tetrandra was entirely due to an inadvertent shipment of Aristolochia fangchi sent in its' stead to a Belgian clinic in 1993. The errant batch of Aristolochia was later confirmed via phytochemical analysis.
Chemistry
Chemical investigation of Stephania rotunda Lour. growing in Vietnam in 2005 led to the isolation and structural elucidation of three new alkaloids, 5-hydroxy-6,7-dimethoxy-3,4-dihydroisoquinolin-1(2H)-one, thaicanine 4-O-beta-D-glucoside, as well as (−)-thaicanine N-oxide (4-hydroxycorynoxidine), along with 23 known alkaloids.
Selected species
There are about 45 species in the genus Stephania, native to the Far East and Australasia. Species include:
