Spectrum Pharmaceuticals

Updated on Nov 10, 2023

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Type Public Website www.spectrumpharm.com		Industry Pharmaceuticals Founded 1987

Traded as NASDAQ: SPPI S&P 600 Component Key people R. Shrotriya, Chief Executive Officer Stock price SPPI (NASDAQ) US$ 6.57 -0.12 (-1.79%)28 Mar, 4:00 PM GMT-4 - Disclaimer CEO Rajesh C. Shrotriya (Aug 2002–) Headquarters Henderson, Nevada, United States Subsidiaries Allos Therapeutics, Talon Therapeutics Inc

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Spectrum Pharmaceuticals is an American biopharmaceutical company. The company is located in Irvine, California.

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Drugs

Spectrum develops and markets drugs for treatments in oncology.

Approved drugs

Fusilev (Levoleucovorin) for injection is a drug that was approved by the U.S. Food and Drug Administration in 2008 for the US; the drug had been on the market in a number of European countries.

Folotyn (pralatrexate) is an antifolate drug marketed for relapsed or refractory peripheral T-cell lymphoma.

Zevalin (ibritumomab) is indicated for the treatment of patients with relapsed or refractory, low‑grade or follicular B‑cell non‑Hodgkin's lymphoma (NHL), including patients with rituximab-refractory follicular NHL. It is a CD-20 radio-antibody.

Marqibo (Vincristine sulfate liposomes injection) is a sphingomyelin/cholesterol liposome-encapsulated formulation of the FDA-approved anticancer drug vincristine. Marqibo's approved indication is for the treatment of adult patients with Philadelphia chromosome-negative acute lymphoblastic leukemia (Ph- ALL) in second or greater relapse or whose disease has progressed following two or more lines of anti-leukemia therapy. It was approved by the FDA in 2012.

Beleodaq (belinostat) is an HDAC inhibitor for relapsed or refractory peripheral T-cell lymphoma.

Evomela (melphalan) is an alkalyating drug for multiple myeloma.

In development

A number of drugs are currently investigated in clinical trials.

Qapzola (apaziquone) is a synthetic bio-reductive prodrug intended for the treatment of non-invasive bladder cancer that is currently in Phase 3 studies. Allergan invested money in 2008 to help develop this medication further and bring it to the market.

Rolontis (eflapegrastim) is in phase III trials for treatment of chemotherapy-induced neutropenia.

Poziotinib is a quinazoline-based pan-HER inhibitor that blocks signaling through HER tyrosine-kinase receptors including HER1 (erbB1; EGFR), HER2 (erbB2), and HER4 (erbB4). It is currently in phase II trials.

Spectrum terminated the development of Ozarelix, a luteinizing hormone releasing hormone antagonist for the treatment of benign prostatic hypertrophy in 2010. Other previous drug candidates included ortataxel for the treatment of taxane-refractory tumors, and satraplatin for non-small cell lung cancer.

References

Spectrum Pharmaceuticals Wikipedia

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