Soulsby may refer to:Ben Soulsby, lumbermill owner and founder of Soulsbyville, California, USA
Henry Soulsby, builder of the 1926 Soulsby Service Station on U.S. Route 66 in Mount Olive, Illinois.
Lawson Soulsby, Baron Soulsby of Swaffham Prior (born 1926), British microbiologist and parasitologist
Sir Peter Soulsby (born 1948), British politician, Mayor of Leicester
Sir William Soulsby (1851–1937), English barrister, Private Secretary to the Lord Mayor of London