Dr. Sohrab Rohani, is a Professor and former Chairman of Department of Chemical and Biochemical Engineering at Western University was named a recipient of the Engineering Medal – Research and Development Category.
Professor Rohani’s main areas of research are Crystallization of Pharmaceuticals (polymorphism) and Process Control.
B.Sc. (Shiraz University, Iran) 1973Ph.D. (University of Wales, Britain) 1977 "You should've done your review paper before you started your degree""If you didn't publish that means you were never here""As a chemical engineer if you don't understand chemistry it makes you a lousy mechanical engineer"Sabouni, R; Kazemian, H. and S. Rohani, Mathematical Modeling and Experimental Breakthrough Curves of Carbon Dioxide Adsorption on Metal Organic Framework CPM-5, Environmental Science & Technology, accepted June 2013.Ragab, D. and S. Rohani, Cubic magnetically guided nanoaggregates for inhalable anticancer drug delivery: In vitro magnetic aerosol deposition study, AAPS PharmSciTech, (DOI) 10.1208/s12249-013-9980-y, accepted May 2013 (impact factor 1.43).Dehnavi, V.; Luan, B.; Shoesmith, D.; Liu, X.Y. and S. Rohani, Effect of duty cycle and applied current frequency on plasma electrolytic oxidation (PEO) coating growth behavior, Surface and Coatings Technology, Ms. Ref. No.: SURFCOAT-D-13-00119R1, accepted March 2013.Sabouni, R; Kazemian, H. and S. Rohani, Carbon Dioxide Adsorption in Microwave- Synthesized Metal Organic Framework CPM-5: Equilibrium and Kinetics study, Microporous & Mesoporous Materials, 175(July) 85-91 (2013).Sheikholeslamzadeh, E. and S. Rohani, Modeling and Optimal Control of Solution Mediated Polymorphic Transformation of L-glutamic Acid, I&ECR, 52(7), 2633-2641(2013) (impact factor 2.01).• Mirmehrabi, M. and S. Rohani, Corrections for "Thermodynamic Modeling of Activity Coefficient and Prediction of Solubility. Parts1 and 2", Journal of Pharmaceutical Sciences vol 95, No 4, 2006, pages 790-809", J. Pharm. Sci., 102(3), 786 (2013).
Hossein Kazemian, H.; Turowec, B.; Siddiquee, M.N. and S. Rohani, Biodiesel Production Using Cesium Modified Mesoporous Ordered Silica as Heterogeneous Base Catalyst, Fuel, 103, 719-724 (2013). (impact factor=3.248).Sheikholeslamzadeh, E.; Chen, C-C; and S. Rohani, Optimal Solvent Screening for the Crystallization of Pharmaceutical Compounds from Multi-solvent Systems, I&ECR, 51(42), 13792-13802 (2012).Wu, L.; Beaurgard, Y.; Qin, Z.; Rohani, S. and D. W. Shoesmith, A model for the influence of steel corrosion products on nuclear fuel under permanent disposal conditions, Corrosion Sci. (61), 83-91 (2012) . (impact factor=3.734).Lu, J.; Yi-Ping Li, Y-P; Wang, J.; Li, Z.; Rohani, S. and C-B Ching, Crystallization of an active pharmaceutical ingredient that oils out. Separation and Purification Technology, (96), 1-6 (2012). (impact factor=2.921).Mao, S.; Zhang, Y.; Rohani, S. and A. K. Ray, Chromatographic Resolution and Isotherm Determination of (R,S)-Mandelic Acid on Chiralcel-OD Column, Journal of Separation Science, 35(17), 2273-2281 (2012). (impact factor=2.733).Ragab, D; Rohani, S. and S. Consta, Controlled Release of 5-Fluorouracil and Progesterone from Magnetic Nano-Aggregates, Int. J. Nanomed., (7) 3167-3189 (2012) (impact factor=4.976).Lu, J.; Wang, J.; Li, Z. and S. Rohani, Characterization and pseudopolymorphism of L-phenylalanine anhydrous and monohydrate forms. African Journal of Pharmacy and Pharmacology, 6(4), 269-277 (2012).Lu, Jie; Li, Yi-Ping; Li, Q; Li, Z; and S. Rohani, Sohrab, Solubility of L-Phenylamine Anhydrous and Monohydrate Forms: Experimental Measurements and Prediction, CJ. Chem. & Eng. Data 57(5), 1492-1498 (2012).Trifkovic, M.; Rohani, S. and M. Sheikhzadeh, Kinetics Estimation and Polymorphic Transformation Modeling of Buspirone Hydrochloride, J. Cryst. Process Technol., 2(2), 31-43 (2012).Zhao, Yingying; Yuan, Junsheng; ji, zhiyong; Wang, Jingkang; ROHANI, S, The Combined Application of in-situ FBRM, ATR-FTIR and Raman on Polymorphism Transformation Monitoring during the Cooling Crystallization, I&ECR, 51(38), 12530-12536 (2012).Sheikholeslamzadeh, E. and S. Rohani, FPE-D-12-00237R1, Vapour-Liquid and Vapour-Liquid-Liquid Equilibrium Modeling for Binary, Ternary, and Quaternary Systems of solvents Fluid Phase Equilibria, Fluid Phase Equilibria (333) 97-105 (2012). (impact factor=2.139).Rohani, S.; Isimjan, T.; Mohamed, A.; Kazemian, H.; Salem, M and T. Wang, Fabrication, modification and environmental applications of TiO2 nanotube arrays (TNTAs) and nanoparticles, Frontiers of Chem. Eng., 6(11), 112-122 (2012).Peng, Y.; He, Q.; Rohani, S. and H. Jenkins, Resolution of 2-chloromandelic acid with (R)-(+)-N-Benzyl-1-Phenylethylamine: Chiral Discrimination Mechanism, Chirality, 24(5), 349-355 (2012). (impact factor= 2.892).Herrera, J. E.; Isimjan, T. T.; Abdullahi, I.; Ray, A. K. and S. Rohani, A novel nanoengineered VOx catalyst supported on highly ordered TiO2 nanotube arrays for partial oxidation reactions, Applied Catal. A, 417-418, 13-18 (2012).Isimjan, T.; Zhu Yan; D.-Q Yang; S. Rohani and A. K. Ray, A new approach of tailoring wetting properties of TiO2 nanotubular surfaces, Advanced Sci Letters, 18, 158-163 (2012). (impact factor=1.25).Isimjan, T.; Wang, T.; and S. Rohani, A Novel Method to Prepare Superhydrophobic, UV Resistance and Anti-corrosion" has been accepted for publication in Chemical Engineering Journal, 210, 182-187 (2012) . (impact factor=3.461).Gordon, J.; Kazemian, H. and S. Rohani, Rapid and efficient crystallization of MIL-53(Fe) by ultrasound and microwave irradiation, Microporous & Mesoporous Materials, 162, 36–43 (2012).Ahmadi, S.; M. Manteghian; H. Kazemian; S. Rohani; J. Towfighi Darian, Synthesis of silver nano catalyst by gel-casting using response surface methodology, Powder Technol., 228,163-170, (2012).Lu, J.; Yi-Ping Li, Y-P; Wang, J.; Li, Z.; Rohani, S. and C-B Ching, Study on the oiling-out and crystallization for the purification of idebenone, Organic Process Research & Development, 16(3), 442-446 (2012).Lu, J.; Wang, J. and S. Rohani, Preparation and characterization of amorphous, I and II forms of clopidogrel hydrogen sulfate. Crystal Research and Technology, 47(5), 505-510 (2012).Zhao, Y. Y.; Sohrab Rohani *, Y. Bao, J.k. Wang *, Characterizing the Polymorphic Transformation of Carbamazepine Using FBRM, ATR-FTIR and Raman, Pharmaceutics, 4, 164-178 (2012).Sheikholeslamzadeh, E. and S. Rohani, Solubility Prediction of Pharmaceutical and Chemical Compounds in Pure and Mixed Solvents Using Predictive Models, I&ECR 51(1), 464-473 (2012).He, Q.; S. Rohani; Zhu, J. and H. Gomaa, Resolution of Sertraline with (R)-Mandelic Acid: Chiral Discrimination Mechanism Study, Chirality, 24(2), 119-128 (2012).Isimjan, T.; Rohani, S.; and A. K. Ray, Photoelectrochemical Water Splitting for Hydrogen Generation on Highly Ordered TiO2 Nanotubes Fabricated by Using Ti as Cathode, Int. J. Hydrogen Energy, 37(1), 103-108 (2012).Trifkovic M.; M. Sheikhzadeh; K. Choo and S. Rohani, Model Predictive Control of a Twin-Screw Extruder for Thermoplastic Vulcanizate (TPV) Applications, Comp. & Chem. Eng., 36, 247-254 (2012).Dargahi, M.; Kazemian, H.; Soltanieh, M.; Hosseinpoor,M. and S. Rohani,High Temperature Synthesis of SAPO-34: Applying an L9 Taguchi Orthogonal Design to Investigate the Effects of Experimental Parameters, Powder Technology, (217) 223-230 (2012).
Siddiquee, M., Kazemian, H. and S. Rohani, Lipid, Biodiesel, FAME, Mesoporous Heterogeneous Catalyst, Chem. Eng. & Technol., 34(12), 1983-1988 (2011).Wang, T.; X. Tao; X. Zeng; Z. Shen; J. Chen and S. Rohani, Layer-by-layer Assembly of Highly Transparent SiO2/TiO2 Coatings with Antireflection and Self-Cleaning Properties, Advanced Sci. Letters, 4(11/12), 3617-3623 (2011).Hu, Y.; Kazemian, H.; Roani, S.; Huang, Y. and Y. Song, In-Situ High Pressure Study of ZIF-8 by FTIR Spectroscopy, Chem. Comm., 47(47), 12694-12696 (2011).Lu, Jie; Jiang, Xiao-Lin; Li, Zhen; Rohani, Sohrab; Ching, Chi-Bun, Solubility of a Lysozyme in Polyelectrolyte Aqueous Solutions, J. Chem. & Eng. Data, 56(12), 4808-4812 (2011).Lu, Jie; Li, Yi-Ping; Wang, Jing; Li, Zhen; Rohani, Sohrab; Ching, Chi-Bun, Pharmaceutical cocrystals: a comparison of sulfamerazine with sulfamethazine, J. Crystal Growth, 335(1), 110-114 (2011).Dargahi, M.; H. Kazemian; M. Soltanieh and S. Rohani, Hosseinpoor, M. Rapid and Efficient High Temperature Synthesis of SAPO-34 Nano Particles Particuology, 9(5), 452-457 (2011).Siddiquee, M. and S. Rohani, Lipid Extraction and Biodiesel Production from Municipal Sewage Sludges - A Review, LLK1700, Fuel Process. Technol., 92, 2241-2251 (2011).Wang, T.; T. Isimjan; J. Chen and S. Rohani, Transparent Nanostructured Coatings with UV-shielding and Superhydrophobicity Properties, Nanotechnol., 22(26) 265708/1-265708/7, (2011) (impact factor=3.98).Kaliyaperumal, S.; S. Barghi; J. Zhu; L. Briens and S. Rohani, Effects of acoustic vibration on nano and sub-micron powders fluidization, Powder Technol, 9(3), 279-287 (2011).Kaliyaperumal, S; S. Barghi; L. Briens; S. Rohani and J. Zhu, Fluidization of nano and sub-micron powders using mechanical vibration, Powder Technol, 210(2), 143-149 (2011).Lu, J.; A. J. Cruz-Cabeza,; S. Rohani and M. C. Jennings, A 2:1 Sulfamethazine:Theophylline Cocrystal Exhibiting two Tautomers of Sulfamethazine, Acta Crystall. Section C, C67(8), o306-o309 (2011).Haja Hameed, A. S., C. Karthikeyan, G. Ravi and S. Rohani, Caharacteriation studies on the additives mixed L-arginne phosphate monohydrate (LAP) crystals, Physica B, 406, 1363-1367 (2011).Mohamed, A. and S. Rohani, Modified TiO2 Nanotube Arrays (TNTAs): Progressive Strategies towards Visible Light Responsive Photoanode, Energy & Envir. Sci., 4, 1065-1086 (2011).Isimjan, T.T.; D.-Q Yang; S. Rohani and A.K. Ray, An Innovative Approach to Synthesize Highly-Ordered TiO2 Nanotubes, J. Nanosci. & Nanotech., 11, 1079-1083 (2011).Siddiquee, M. and S. Rohani, Lipid Extraction and Biodiesel Production from Municipal Sewage Sludges - A Review, LLK1700, Renewable and Sustainable Energy Reviews, 15, 1067–1072 (2011).Lu, J.; Z. Li; X. Jiang and S. Rohani, Solubility of L-phenylalanine in aqueous solutions J. Chem. Eng. Japan, 43(8-12), 810-813 (2010).He, Q.; S. Rohani; J. Zhu and H. Gomaa, Crystallization of Racemic Compound and Conglomerate of (RS)-2-Chloromandelic acid, Crystal Growth & Des., 10(12), 5136-5145 (2010).Isimjan, T.T.; H. Kazemian; S. Rohani and A.K. Ray, Photo catalytic activities of Pt/ZIF-8 loaded highly ordered TiO2 nanotube, J. Materials Chemistry, 20(45), 10241-10245, (2010).Prakash, A.; A. Shukla and S. Rohani, Ultrasonic method of monitoring particle size distribution of a medium, 147, PCT Int. Appl., (2010).Shukla, A; A. Prakash and S. Rohani, Particle size distribution measurements in dense suspensions using ultrasonic spectroscopy with an improved model accounting for low angle scattering, AIChE J., 56(11), 2825-2837, (2010).Mao, S; Y. Zhang; S. Rohani and A.K. Ray, Kinetics of (R,S)- and (R)-Mandelic Acid in an Unseeded Cooling Batch Crystallizer, J. Crystal Growth, (312) 3340-3348 (2010).Zhang, Y; S. Mao; A. K. Ray and S. Rohani, Nucleation and Growth Kinetics of (R)-Mandelic Acid from Aqueous Solution in the Presence of Opposite Enantiomer, Crystal Growth & Des., 10(7), 2879-2887 (2010).Sabouni, R; H. Kazemian and S. Rohani, A novel combined manufacturing technique for rapid production of IRMOF-1 using ultrasound and microwave energies Chem. Eng. J. 165, 966-973 (2010).He, Q.; S. Rohani, J. Zhu and H. Gomaa, Sertraline Racemate and Enantiomer: Solid-State Characterization, Binary Phase Diagram and Crystal Structures, Crystal Growth & Des. 10(4), 1633-1645 (2010).Shukla, A; A. Prakash and S. Rohani, Online Measurement of Particle Size Distribution during Crystallization using Ultrasonic Spectroscopy, Chem. Engng Sci., 65(10), 3072-3079, (2010).Isimjan, T.T.; A.M. ElRuby; S. Rohani and A.K. Ray, Fabrication of highly-ordered and visible-light responsive Fe-C-N-codoped TiO2 nanotubes, Nanotechnol., 21(5), 055706/1-055706/6, (2010).Rohani, S. Applications of the Crystallization Process in the Pharmaceutical Industry, Frontiers of Chemical Engineering in China, 4(1), 2-9 (2010).Trifkovic M.; M. Sheikhzadeh; K. Choo and S. Rohani, Experimental and Statistical Study of the Effects of Material Properties, Curing Agents and Process Variables on the Production of hermoplastic Vulcanizates, J Applied Polymer Sci., 118(2), 764-777(2010).He, Q.; H. Gomaa; S. Rohani; J. Zhu and M. Jennings, Chiral Discrimination of Diastereomeric Salts of Chlorine-Substituted Mandelic Acid and Phenylethylamine, Chirality, 22(8), 707-716, (2010).Trifkovic M.; M. Sheikhzadeh; K. Choo and S. Rohani, Model Identification of a Twin Screw Extruder for Thermoplastic Vulcanizate (TPV) Applications, Polymer Eng. and Sci., 50(6), 1168-1177 (2010).Lu, J. and S. Rohani, Synthesis and preliminary characterization of sulfamethazine-theophylline co-crystal, J. Pharm. Sci. 99(9), 4042-4047 (2010).Ragab, D.; S. Rohani; M. W. Samaha; F. M. El-Khawas and H. A. El-Maradny, Crystallization of Progesterone for Pulmonary Drug Delivery, J. Pharm. Sci., 99(3), 1123-1137 (2010).He, Q.; Y. F. Peng and S. Rohani, Diastereomeric Resolution of p-Chloromandelic Acid with (R)-Phenylethylamine, Chirality, 22(1), 16-23 (2010).Mohamed, A. E.; N. Kasemphaibulsuk; S. Rohani and S. Barghi, Fabrication of Titania Nanotube Arrays in Viscous Electrolytes, J. Nanosci. Nanotechnol. 10 (3), 1998-2008 (2010).Zhang, Y.; A. K. Ray and S. Rohani; Measurement and Prediction of Phase Diagrams of the Enantiomeric 3-Chloromandelic Acid System: CES8236, Chem. Engng Sci., 64(2), 192-197 (2009).Trifkovic, M.; M. Sheikhzadeh and S. Rohani, Multi-Variable Real Time Optimal Control of a Cooling and Anti-solvent Semi-Batch Crystallization Process, AIChE J.,55(10), 2591-2602 (2009).Ragab, D. and S. Rohani, Particle Engineering Strategies via Crystallization for Pulmonary Drug Delivery, Org. Proc. Res. Dev., 13(6), 1215-1223 (2009).Lu, J. and S. Rohani, Polymorphism and Crystallization of the anti-viral/HIV drug stavudine, Org. Proc. Res. Dev., 13(6), 1262-1268 (2009).Trifkovic M.; M. Sheikhzadeh and S. Rohani, Determination of Metastable Zone Width for Combined Anti-solvent/Cooling Crystallization, J. Crystal Growth, 311(14), 3640-3650 (2009).Bakhbakhi, Y.; P. Charpentier and S. Rohani, The Solubility of Beclametasone-17,21dipropionate in Selected Organic Solvents: Experimental Measurements and Thermodynamic Modeling, Org. Proc. Res. Dev., 13(6), 1322-1326 (2009).He, Q.; J. Zhu, H. Gomaa, M. Jennings and S. Rohani, Identification and Characterization of Solid-State Nature of 2-Chloromandelic Acid, J. Pharm. Sci., 98(5), 1835-1844 (2009).Knox, M.; M. Trifkovic and S. Rohani, Combining Anti-Solvent and Cooling Crystallization: Effect of Solvent Composition on Yield and Meta Stable Zone Width, Chem. Engng Sci., 64, 3555-3563 (2009).Lu, J. and S. Rohani, Preparation and Characterization of Theophylline-Nicotinamide Cocrystal, Org. Proc. Res. Dev., 13(6) 1269-1275 (2009).Karami, D. and S. Rohani, Synthesis of Pure Zeolite Y Using Soluble Silicate, A Two-Level Factorial Experimental Design, Chem. Eng. and Processing, 48, 1288–1292 (2009).Karami, D. and S. Rohani, A Novel Approach for the Synthesis of Zeolite Y, Ind. Eng. Res. Dev., 48(10), 4837-4843 (2009).Lu, J. and S. Rohani, Polymorphism and Crystallization of Active Pharmaceutical Ingredients (APIs), Current Medicinal Chemistry, 16, 884-905 (2009).Hojjati, H. and S. Rohani, A New Approach for Isothermal Calorimetric Technique”, Reg. No.9165, J Thermal Analysis and Calorimetry, 95(1), 293–303, (2009).Corriou, J. P. and S. Rohani, AIChE-07-10610.R2 - A new look at optimal control of a batch crystallizer, AIChE J., 54(12), 3188-3206 (2008).Zhang, Y.; S. Rohani and A. K. Ray, Numerical determination of competitive adsorption isotherm of mandelic acid enantiomers on cellulose-based chiral stationary phase, JCA07-2318, J. Chromatography A, 34-39, 1202 (2008).Trifkovic, M.; M. Sheikhzadeh and S. Rohani, Parameter Estimation and Single/Multi - Objective Optimization of a Seeded, Anti-solvent, Isothermal Crystallizer, Ind. Eng. Res. Dev., 47, 1586-1595 (2008).Sheikhzadeh, M.; M. Trifkovic and S. Rohani, "Adaptive MIMO Neuro-Fuzzy Logic Control of a Seeded and an Unseeded Anti-Solvent Semi-Batch Crystallizer”, Chem. Engng Sci., 63(5), 1261-1272 (2008).Sheikhzadeh, M., Trifkovic M., Rohani, Real-Time Optimal Control of an Anti solvent, Isothermal Semi-Batch, Crystallizer, Chem. Engng Sci., 63(3), 829-839 (2008).Sheikhzadeh, M.; M. Trifkovic and S. Rohani, Fuzzy Logic and Rigid Control of a Seeded Semi-Batch, Anti solvent, Isothermal Crystallizer, Chem. Engng Sci., 63(4), 991-1002 (2008).He, Q.; M. C. Jennings; S. Rohani; J. Zhu and H. Gomaa, (R)-1-Phenylethanaminium (S)-4-chloromandelate, Acta Crystall., Section E, 64, o559 (2008).Shukla, A.; A. Prakash and S. Rohani, Particles Settling Studies Using Ultrasonic Techniques, Powder Technol. 177(2), 102-111 (2007).He, Q.; M. Jennings; S. Rohani; J. Zhu and H. Gomaa, R-Phenylethylammonium R-4-chloromandelate, Acta Crystall. Section E, E63(11), o4199 (2007).Haja Hameed, A. S.; S. Rohani; W.C. Yu; C.Y. Tai and W. C. Lan, Growth and Characterization of a New Chelating Added 4-dimethylamino-N-methyl-4-stilbazolium tosylate (DAST) single crystals, Materials Chemistry & Physics, 102(1), 60-66 (2007).Sarkar, D.; S. Rohani and A. Jutan, Multi-objective optimization of semi-batch reactive crystallization processes, AIChE J., 53(5), 1164-1177 (2007).Sheikhzadeh, M; Rohani, S; Taffish, M. and S. Murad, Solubility Analysis of Buspirone Hydrochloride Polymorphs: Measurements and Prediction, Int. J. Pharm., 338, 55-63 (2007).Sheikhzadeh M; Rohani S; Jutan A; Manifar T Quantitative and molecular analysis of buspirone hydrochloride polymorphs. Journal Pharmaceutical Sci., 96(3), 569-83, (2007).Hojjati, H.; Sheikhzadeh, M.; Rohani, S. Control of Supersaturation in a Semi-batch Antisolvent Crystallization Process Using a Fuzzy Logic Controller. Industrial & Engineering Chemistry Research 46(4), 1232-1240 (2007).Tifkovic, M.; S. Rohani and M. Mirmehrabi, Polymorphic generation through solvent selection: Ranitidine Hydrochloride, Org. Proc. Res. Dev., 11(1), 138-143 (2007).Mirmehrabi, M., S. Rohani, L. Perry, ‘Thermodynamic Modeling and Prediction of Drug Solubility in Solvents: Part 1. A New Activity Coefficient Model', J. Pharmaceutical Sci., 95(4), 790-797 (2006).Mirmehrabi, M., S. Rohani, L. Perry, ‘Thermodynamic Modeling and Prediction of Drug Solubility in Solvents: Part 2. The New Model, the UNIQUAC and the NRTL Models', J. Pharmaceutical Sci., 95(4), 798-809 (2006)Mirmehrabi, M., S. Rohani, K.S.K. Murthy and B. Radatus, ‘Polymorphic Behaviour and Crystal Habit of an Anti-Viral/HIV Drug: Stavudine', J. Crystal Growth & Des. 6(1), 141-149(2006).Mirmehrabi, M., S. Rohani ‘An Approach to Solvent Screening for Crystallization of Polymorphic Pharmaceuticals and Fine Chemicals', J. Pharmaceutical Sci., 94 (7), 1560-1576 (2005). 