Smith Mead Weed (1834 – June 7, 1920) was a Democratic lawyer and businessman of Plattsburgh, New York. Weed had been a member of the New York State Assembly from Clinton County, New York in 1865, 1866, 1867, 1871, 1873 and 1874; and a delegate to the 1876 and 1884 Democratic National Conventions.
He was a candidate for U.S. Senate in the January 1887 election. He lost to Republican Frank Hiscock.
He was married to Catherine Lester Standish, a descendant of Myles Standish.