Neha Patil (Editor)

Simulations Plus

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Type
  
Public

Industry
  
Software

Founder
  
Walter Woltosz

Traded as
  
NASDAQ: SLP

Number of employees
  
>60

Founded
  
1996

Simulations Plus httpsmedialicdncommediaAAEAAQAAAAAAAAbyAAAA

Products
  
Software GastroPlus ADMET Predictor MedChem Studio DDDPlus MedChem Designer MembranePlus

Website
  
www.simulations-plus.com

Stock price
  
SLP (NASDAQ) US$ 10.70 +0.35 (+3.38%)21 Mar, 4:00 PM GMT-4 - Disclaimer

Headquarters
  
Lancaster, California, United States

Subsidiaries
  
Sage Informatics LLC, Bioreason Inc., Cognigen Corporation

Profiles

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Simulations plus company overview video


Simulations Plus, Inc. develops absorption, distribution, metabolism, excretion, and toxicity (ADMET) modeling and simulation software for the pharmaceutical and biotechnology, industrial chemicals, cosmetics, food ingredients, and herbicide industries. In September 2014, the company acquired Cognigen Corporation, a leading provider of clinical trial data analysis and consulting services.

Contents

Simulations plus company overview


Software programs

The company has produced specific proprietary software products, such as:

  • GastroPlus, a physiologically-based simulation tool that predicts the absorption, pharmacokinetics, pharmacodynamics, and drug-drug interactions for drugs administered through intravenous, oral, ocular, or pulmonary routes. The modeling theory and approach has been discussed in several peer-reviewed publications.
  • ADMET Predictor, a modeling program that enables pharmaceutical researchers to estimate ADMET properties from chemical structure. The performance of the models have been assessed in several peer-reviewed articles.
  • ADMET Modeler, a module of ADMET PredictorTM that allows scientists to build QSAR models using their own data sets.
  • MedChem Studio, a multi-purpose cheminformatics software tool used for advanced data mining and de novo molecule design.
  • DDDPlus, a software tool for formulation scientists that simulates the in vitro disintegration and dissolution of solid dosage forms under different experimental conditions.
  • MedChem Designer, a chemical sketching tool that combines molecule drawing capabilities with ADMET property predictions.
  • MembranePlus, a software program which simulates the in vitro permeability experiments commonly run in the pharmaceutical industry, including Caco-2, PAMPA, and MDCK cell lines.

    • As of March 1, 2015, all of the top 20 pharmaceutical companies, along with the U.S. Food and Drug Administration (FDA), the Centers for Disease Control and Prevention (CDC), the National Institutes of Health (NIH), the National Cancer Institute (NCI) and the China Food and Drug Administration (CFDA) license the company's software.

    References

    Simulations Plus Wikipedia
    (Text) CC BY-SA