Simeon is a surname. Notable people with the surname include:
Albert T. W. Simeons (1900–1970), leading exponent of a weight-loss protocol based on human chorionic gonadotropin (hCG)Arthur Simeon (born 1983), stand-up comedian based in Toronto, CanadaCharles Simeon (1759–1836), English evangelical clergymanCharles Simeon (colonist) (1816–1867), one of the members of the Canterbury Association who emigrated to Canterbury, New ZealandDaphne Simeon, American psychiatristDavid Simeon (born 1943), British actorDoris Simeon, award winning Yoruba and English actressEleazar b. Simeon, Jewish Tanna sage of the fifth generationEric Simeon (1918–2007), Indian school educationalistGeorge Simeon (fl. 1614–1624), English landowner and politician who sat in the House of CommonsJay Simeon (born 1976), Canadian artist of Haida heritageJohn Simeon (disambiguation)José Simeón (born 1991), Spanish basketball playerMbaydoum Simeon, member of the Pan-African Parliament from ChadOmer Simeon (1902–1959), American jazz clarinetistRichard Simeon, 2nd Baronet (1784–1854), English Liberal Party politicianSilvano Simeon (1945–2010), Italian discus throwerSimeon baronets, two baronetcies created for persons with the surname SimeonXavier Siméon (born 1989), Grand Prix motorcycle racer from Belgium