CAS Number 34445-07-3 UNII DDU19UEV1 | ChemSpider 142121 Molar mass 160.9276 g/mol | |
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Trade names Saforide, Advantage Arrest, Cariesop, Bioride, FluoroplatV, Riva Star Legal status US: ℞-only and 510(k) cleared class II medical device Synonyms Diammine Silver Fluoride, Diamine silver fluoride (chemically erroneous) | ||
Silver diammine fluoride sdf application demo
Silver diammine fluoride (also spelled "diamine") is a topical medicament (drug) used to treat and prevent dental caries (cavities) and relieve dentinal hypersensitivity. Silver diammine fluoride has been available in many countries including China, Japan, New Zealand, Australia and others for many decades. The product was cleared for sale in the USA in August 2014 by the FDA as a class II medical device for the treatment of dentinal hypersensitivity.
Contents
- Silver diammine fluoride sdf application demo
- Clinical evidence
- Precautions
- Chemistry and nomenclature
- References
Clinical evidence
6 randomized clinical trials document a effect in arresting cavities, simply by drying the cavity and then applying this material.
2 randomized clinical trials document a profound effect in preventing cavities, by application to other surfaces that have cavities.
4 randomized clinical trials document a profound effect in preventing cavities, simply by drying the tooth surface and then applying this material.
A 2016 systematic review of the scientific literature and protocols for use was published in the California Dental Journal reported:
Silver diammine fluoride stains cavities black. A completely darkened cavity is a strong indicator of success.
Precautions
Silver diammine fluoride will stain most oxidizable surfaces black. Skin and soft tissue will discolor within minutes to hours after contact and fade away (via surface shedding) within a few days. Dentin and enamel with no demineralization present will receive surface (pellicle) stains that can be removed with pumice, while demineralized tooth structure will stain more permanently black. Silver diammine fluoride is corrosive to metal and glass. Contact with metal produces hydrogen gas and hydrogen fluoride while contact with glass will form silicon tetrafluoride. It is a light-sensitive clear liquid with a strong ammonia smell (when there is excess present) and should be stored in a cool, dark, dry place in a plastic container (LDPE or HDPE).
Chemistry and nomenclature
Silver diammine fluoride is a metal ammine complex of silver fluoride. The ammonia ligands are thus "ammine", but the term "amine" is sometimes used for this chemical. In addition to that spelling difference, it is sometimes also called "ammoniacal silver fluoride", which is also sometimes improperly spelled as "ammonical silver fluoride".