Neha Patil (Editor)

Silence Therapeutics

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Type
  
Public (LSE: SLN)

Founded
  
1994

Number of employees
  
50

Industry
  
Pharmaceuticals

Headquarters
  
London, United Kingdom

Silence Therapeutics httpslh4googleusercontentcomPSp7spn1p4AAA

Website
  
www.silence-therapeutics.com

Stock price
  
SLN (LON) 88.00 GBX 0.00 (0.00%)21 Mar, 2:36 PM GMT - Disclaimer

Profiles

Silence Therapeutics (AIM:SLN) is a biotechnology company that develops gene therapeutic technology based on RNA interference (RNAi). They are involved in developmental research of targeted RNAi therapeutics for the treatment of serious diseases. Formed in 1994 as a publicly traded drug research and development company, Silence Therapeutics has offices in London and Berlin, with its corporate headquarters based at 1 Lyric Square, London.

Contents

Profile

The targeting, delivery and ongoing structural modification of sequences are the three platforms for Silence Therapeutics’s RNAi therapeutic development. These three platforms are:

  • proprietary delivery using nanoparticles and lipoplex technology
  • proprietary siRNA sequences complied using bioinformatics algorithms and scientific research
  • development of siRNA structural features
  • Silence Therapeutics develops these structural modifications using three exclusive licences from the University of Massachusetts Amherst.

    History

    In 2005, the company acquired Atugen AG based in Germany, changing the company name to Silence Therapeutics AG. More recently in January 2010, Silence Therapeutics merged with Intradigm Corporation, a privately held biotechnology company in the United States that developed systematic RNA interference.

    Partnerships

    Silence Therapeutics has multiple partnerships with other pharmaceutical companies, such as AstraZeneca, Pfizer/Quark Pharma and Dainippon Sumitomo.

    References

    Silence Therapeutics Wikipedia