Siegler is a surname. Notable people with the surname include:
Edward Siegler (1881–1942), American gymnast and track and field athlete who competed in the 1904 Summer Olympics
M. G. Siegler (born 1981), venture capitalist
Mark Siegler (born 1941), American physician who specialized in internal medicine
Robert S. Siegler (also known as Bob Siegler) is Teresa Heinz Professor of Psychology at Carnegie Mellon University
Sammy Siegler, American rock drummer, notable for his many contributions to the New York hardcore scene