Siegler is a surname. Notable people with the surname include:
Edward Siegler (1881–1942), American gymnast and track and field athlete who competed in the 1904 Summer OlympicsM. G. Siegler (born 1981), venture capitalistMark Siegler (born 1941), American physician who specialized in internal medicineRobert S. Siegler (also known as Bob Siegler) is Teresa Heinz Professor of Psychology at Carnegie Mellon UniversitySammy Siegler, American rock drummer, notable for his many contributions to the New York hardcore scene