Nationality Indian Doctoral advisor Roberta Colman Academic advisor Roberta Colman | Fields Structural biology Field Structural biology | |
Born April 1, 1954
West Bengal, India ( 1954-04-01 ) Known for Studies on gene expression using the operator-repressor system of bacteriophage lambda
macromolecular interactions leading to high fidelity of protein synthesis Notable awards 1999 Shanti Swarup Bhatnagar Prize
USDHHS Meritorious Service Award Alma maters Presidency University, Kolkata, University of Delaware, Brandeis University Institutions Indian Institute of Chemical Biology, Bose Institute, NIH | ||
The public focused scientist engineer siddhartha roy tedxvirginiatech
Siddhartha Roy (born 1954) is an Indian structural biologist, biophysicist and the Director of the Indian Institute of Chemical Biology. Known for his studies on bacteriophage lambda and protein synthesis, he is a former faculty at Bose Institute and an elected fellow of the Indian Academy of Sciences and the Indian National Science Academy. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 1999, for his contributions to biological sciences.
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Biography
Born on the 1st April 1954 in the Indian state of West Bengal, Siddhartha Roy obtained an honours degree in chemistry (BSc Hons) from Presidency College, Calcutta in 1974 and did his doctoral studies at the University of Delaware under the guidance of Prof. Roberta Colman to secure a PhD in 1981. His post-doctoral studies were at Brandeis University at the laboratory of Prof. Alfred Redfield (1981–82) and at the National Institutes of Health (1982–86). Returning to India in 1986, he joined Bose Institute, Kolkata as a Senior Lecturer in the department of Biophysics. He served the Institute till 2004 holding positions of Reader and then Professor of Biophysics when he moved to the Indian Institute of Chemical Biology (IICB) as its Director. After completing 10 years as the Director of IICB, he returned to Bose Institute in 2014 as a Senior Professor and Dean of studies. While at IICB, he has served the nation in several different high level capacities such as the Founder-Director-in-charge of the National Institute of Pharmaceutical Education and Research, Kolkata (NIPER) (2007–14), the Cluster Director of 11 Biological institutes of the Council of Scientific and Industrial Research (CSIR) (2009–14), member of the Governing Body of the CSIR and as a Visiting Professor at Osaka University (2012).He also served as the President of the West Bengal Academy of Science and Technology. He is the Founder-President of the Chemical Biology Society of India. He currently serves as a member of the Board of Governors of the International Chemical Biology Society. He is currently the Director (officiating) of Bose Institute.
Legacy
Roy's researches during his stint in the US was on protein folding and nuclear magnetic resonance studies of DNA and those researches identified the first hydropathy model which helped in predicting the exteriors and interiors of proteins by analyzing sequence information. He is also reported to have performed the complete assignment of a nucleic acid imino proton spectra using Nuclear Overhauser Effect, regio-specific isotope labeling of sugars in nucleic acids and working along with Ad Bax and R. H. Griffey, developed an indirect 2D-NMR detection method, all reported to be for the first time. Later focusing his attention on bacteriophage lambda, he studied the gene expression of the bacterial virus using its operator-repressor system. Through his collaborative work with Sankar Adhya in 1998, he elucidated the role of differential contact in the transcription regulation mechanism and demonstrated the theory in many genetic regulatory circuits. His current work is focused on peptide therapeutics and he holds patents for some of his work.
Roy has published his research work through a number of articles published in peer-reviewed journals and ResearchGate, an online repository of scientific papers, has listed 155 of them. He is a joint editor of Subcellular Biochemistry, volume on Proteins: Structure, Function, and Engineering published by Plenum Press, New York, USA. He has guided around 30 scholars in their doctoral studies. When the Chemical Biology Society of India was formed in 2013, he became its founder president and holds the position. He is a former president of the West Bengal Academy of Science and Technology and is its incumbent vice president.
Awards and honors
The Indian Academy of Sciences elected Roy as their fellow in 1996 and the Council of Scientific and Industrial Research awarded him the Shanti Swarup Bhatnagar Prize, one of the highest Indian science awards, in 1999. A recipient of the Meritorious Service Award of the United States Department of Health and Human Services, he was elected by the Indian National Science Academy as a fellow in 2005. In 2007, he was elected as a fellow of the West Bengal Academy of Science and Technology and he received the J. C. Bose National Fellowship of the Science and Engineering Research Board as well as the Tata Innovation Fellowship of the Department of Biotechnology the same year. He was also a member of Guha Research Conference during the years 1992 and 2012.He is also a Fellow of the Royal Society of Chemistry, UK.
Patents
The list is incomplete.