Sharkey (Irish: Ó Searcaigh) is a surname of Irish origin. Notable people with the surname include:
Bill Sharkey (1873–1946), Australian rules footballer
Brendan Sharkey (born 1962), American politician
Catherine Sharkey (born c. 1970), law professor
Ed Sharkey (born 1927), American former National Football League player
Feargal Sharkey (born 1958), lead singer of the pop punk band The Undertones
Jack Sharkey (1902-1994), American heavyweight boxing champion
James A. Sharkey (born 1945), Irish historian and diplomat
Jim Sharkey (1934-2014), Scottish footballer
Joe Sharkey, columnist for The New York Times
John Sharkey, Baron Sharkey (born 1947), British politician
Jonathon Sharkey (born 1964), American professional wrestler and perennial candidate
Kevin Sharkey (born 1961), Irish artist
Lance Sharkey (1898-1967), Australian trade union activist, radical journalist and communist politician
Michael Sharkey (born 1946), Australian poet, biographer, reviewer and academic
Nick Sharkey (1943-2015), Scottish footballer
Noel Sharkey, British computer scientist
Pat Sharkey (born 1953), former footballer from Northern Ireland
Paul Sharkey (born 1974), former Australian rules footballer
Ray Sharkey (1952-1993), American actor
Seymour Sharkey (1847–1929), British physician
Tom Sharkey (1873-1953), American boxer
William L. Sharkey (1798-1873), American judge and politician
William J. Sharkey (US Navy officer) (1885-1918)
William J. Sharkey (murderer) (c. 1847-?), convicted murderer and minor New York City politician
Fictional characters include:
Captain John Sharkey, a fictional pirate, the main character of Sir Arthur Conan Doyle's 1925 novel The Dealings of Captain Sharkey
Francis Ethelbert Sharkey, a character in the television series Voyage to the Bottom of the Sea portrayed by Terry Becker
C.P.O. Sharkey, the title role of a 1976 to 1978 American television series, played by Don Rickles
Finn Sharkey, character in UK TV series Waterloo Road
Sharkey, right hand man of Olrik in Blake and Mortimer, Franco-Belgian comics