Routes of
administration Oral CAS Number 57262-94-9 Molar mass 261.36 g/mol ChemSpider ID 5016 | ATC code none PubChem CID 5205 Pubchem 5205 | |
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AHFS/Drugs.com International Drug Names Legal status In general: ℞ (Prescription only) | ||
Setiptiline (Tecipul), also known as teciptiline, is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). It was launched in 1989 for the treatment of depression in Japan by Mochida.
Contents
Chemistry
Setiptiline has a tetracyclic structure and is a close analogue of mianserin and mirtazapine, with setiptiline being delta(13b,4a),4a-carba-mianserin, and mirtazapine being 6-aza-mianserin.
Pharmacology
Setiptiline acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes, as well as an H1 receptor inverse agonist/antihistamine.
References
Setiptiline Wikipedia(Text) CC BY-SA