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A Sertoli cell nodule, also Pick's adenoma, testicular tubular adenoma and tubular adenoma of the testis, is a benign proliferation of Sertoli cells that arises in association with cryptorchidism (undescended testis). They are not composed of a clonal cell population, i.e. neoplastic; thus, technically, they should not be called an adenoma.
Pathology
Sertoli cell nodules are unencapsulated nodules that consist of:
- cells arranged in well-formed tubules (that vaguely resemble immature Sertoli cells), with
- bland hyperchromatic oval/round nuclei that are stratified, and
- may contain eosinophilic (hyaline) blob in lumen (centre).
References
Sertoli cell nodule Wikipedia(Text) CC BY-SA