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Serous carcinoma

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Serous carcinoma

In pathology, serous carcinoma is an epithelial malignancy (carcinoma) that arises from the lining of a cavity that produces a serum-like fluid (a serous cavity).

Contents

Serous lined cavities include the peritoneum, pericardium and pleural space and tunica vaginalis.

Cytologic features

Cytologic features of serous carcinoma are:

  • Marked intragroup nuclear pleomorphism.
  • Macronucleoli.
  • "Knobby" group borders (in large groups).
  • Hydropic vacuoles.
  • Symptoms of serous carcinoma may include:

  • Discomfort/pain or bloating in abdomen
  • Frequent urination
  • Weight loss
  • Differential diagnosis

    The differential diagnosis of serous carcinoma not otherwise specified includes:

  • Ovarian serous carcinoma, a type of ovarian cancer.
  • Uterine serous carcinoma, also known as uterine papillary serous carcinoma, a type of uterine cancer.
  • Fallopian tube serous carcinoma, a type of uterine tube cancer.
  • Cervical serous carcinoma, a rare type of cervical cancer.
  • Primary peritoneal serous carcinoma, a very rare cancer that arise from the peritoneum.
  • There has been the suggestion that the above diagnoses really represent one entity.

    References

    Serous carcinoma Wikipedia


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