Seccombe or Secombe is a surname. Notable people with the surname include:
Alf Seccombe (born 1982), American filmmaker
Andy Secombe (born 1953), Welsh actor and author
Don Seccombe (born 1942), Australian cricketer
Fred Secombe (born 1918), Welsh priest
Harry Secombe (1921–2001), Welsh comedian and singer
James Seccombe (1893–1970), American politician
Joan Seccombe, Baroness Seccombe (born 1930), British peer
Pauline Seccombe, maiden name of Pauline Hanson (born 1954), Australian politician
Philip Seccombe, British politician
Thomas Seccombe (1866–1923), English writer
Victor Secombe (1897–1962), Australian general
Wade Seccombe (born 1971), Australian cricketer
