Seccombe or Secombe is a surname. Notable people with the surname include:
Alf Seccombe (born 1982), American filmmakerAndy Secombe (born 1953), Welsh actor and authorDon Seccombe (born 1942), Australian cricketerFred Secombe (born 1918), Welsh priestHarry Secombe (1921–2001), Welsh comedian and singerJames Seccombe (1893–1970), American politicianJoan Seccombe, Baroness Seccombe (born 1930), British peerPauline Seccombe, maiden name of Pauline Hanson (born 1954), Australian politicianPhilip Seccombe, British politicianThomas Seccombe (1866–1923), English writerVictor Secombe (1897–1962), Australian generalWade Seccombe (born 1971), Australian cricketer