Sean or Seán Ryan may refer to:
Seán Ryan (politician) (born 1943), Irish Labour Party politicianSean Ryan (American politician), New York state legislatorSeán Ryan (Irish fiddler) (died 1985), Irish folk music fiddlerSeán Ryan (Irish judge), President of the Court of Appeal (Ireland) and chair of the Commission to Inquire into Child AbuseSean Ryan (American football) (born 1980), tight end in the National Football LeagueSean Ryan (rugby league) (born 1973), Australian former rugby league playerSean Ryan (swimmer) (born 1992), American swimmerSean Ryan (American football coach) (born 1972), American football coach and former playerSeán Ryan (GAA President), president of the Gaelic Athletic Association