Scoulerine

Scoulerine, also known as discretamine and aequaline, is a benzylisoquinoline alkaloid that derives from reticuline and is a precursor of berberine. It is found in many plants, including Opium poppy, Croton flavens, and certain plants in the Erythrina genus.

Studies show that scoulerine is an antagonist in vitro at the α₂-adrenoceptor, α_1D-adrenoceptor and 5-HT receptor. It has also been found to be a GABA_A receptor agonist in vitro.