Neha Patil (Editor)

Satratoxin H

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Formula
  
C29H36O9

Satratoxin-H httpsuploadwikimediaorgwikipediacommonsbb

Satratoxin-H, a trichothecene mycotoxin, is a naturally occurring toxin produced by the ascomycetes Stachybotrys chartarum and Podostroma cornu-damae which is toxic to humans and animals. The clinical condition it causes is known as Stachybotrotoxicosis. It is related to the mycotoxin T-2, but unlike T-2 has not been reported to have been used as a biological weapon.

Contents

Properties

Satratoxin-H is almost completely insoluble in water, but is easily soluble in lower alcohols and polar solvents such as ethanol, methanol, isopropanol (rubbing alcohol), acetone and chloroform.

Satratoxin-H is not officially classified as a chemical weapon.

Effects

Satratoxin-H is extremely versatile. Contact with the solution through ingestion, inhalation, or even physical contact produces symptoms similar to those listed below.

  • a rash that becomes a moist dermatitis
  • nosebleeds
  • chest pain
  • pulmonary hemorrhage (bleeding in the lungs)
  • hyperthermia (raised temperature)
  • headache
  • fatigue
  • However, if consumed in large quantities, it can be lethal. Satratoxin-H has little effect on bare skin, and does not blister in the way many chemical weapons do. However, upon sensitive surfaces (eyes, interior of mouth or nose), it can irritate the skin or cause a rash.

    The toxicology of satratoxin-H shows that it has an LD50 for mice of 1.0-1.4 mg/kg, upon injection. Otherwise it is reported to be about five times as toxic as the T-2 toxin.

    References

    Satratoxin-H Wikipedia