Name Sarah Tishkoff | ||
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Sarah tishkoff u pennsylvania part 1 african genomics human evolution
Sarah A. Tishkoff (born 1965) is an American geneticist who is the David and Lyn Silfen Professor at the University of Pennsylvania. One of her focuses is the genetic history of African populations, including the causes for lactose persistence among some African population groups.
Contents
- Sarah tishkoff u pennsylvania part 1 african genomics human evolution
- Sarah tishkoff u pennsylvania part 3 african genomics natural selection
- Education and career
- Research
- Awards
- References
Sarah tishkoff u pennsylvania part 3 african genomics natural selection
Education and career
Tishkoff received a Bachelor of Science degree with a focus on anthropology and genetics from the University of California, Berkeley in 1989, a Master of Science degree in human genetics from Yale University in 1992 and achieved a PhD in genetics from Yale in 1996 with Kenneth Kidd as her advisor.
Tishkoff was a fellow at Pennsylvania State University from 1997–2000 and worked as an assistant professor and later associate professor at the University of Maryland from 2000–2007. She became an associate David and Lyn Silfen University Professor at the University of Pennsylvania in 2008 and a full professor in 2012.
Research
Tishkoff was lead writer of the 2007 paper "Convergent adaptation of human lactase persistence in Africa and Europe" which was published in Nature Genetics. The paper documented three new single-nucleotide polymorphisms (SNPs) for lactase persistence among ethnic groups in East-Africa. These mutations were different from the mutation for lactose tolerance that is common in Europe (C/T-13910) . The most widespread mutation was found among Nilo-Saharan speaking groups in Tanzania and Kenya while two independent mutations were found among the Beja people in Sudan and Afroasiatic speaking people in Kenya. The SNPs did not however fully explain the ability among some African persons to digest milk. A 2014 study published in American Journal of Human Genetics documented two more SNPs that could be linked to lactose tolerance, although causation was not firmly established. The study also found the European variant C/T-13910 among some pastoralist groups in Northern and Central Africa.
Awards
