Sanford is a surname. Notable people with the surname include:
Adam Sanford, Dominican cricketerAgnes Sanford, American Christian writerArlene Sanford, American film and television directorChance Sanford, American baseball playerCharles S. Sanford, Jr., American businessmanChris Sanford (born 1968), American retired mixed martial artistCurtis Sanford, Canadian ice hockey goaltenderDonald Sanford, American-Israeli Olympic sprinterEdmund Sanford, American psychologistEdward Sanford, New York politicianEdward Terry Sanford, U.S. Supreme Court justiceFred Sanford, American baseball playerFred Sanford, American musicianGarwin Sanford, Canadian actorHenry Shelton Sanford, American diplomat and businessman, founder of the city of Sanford, Florida.Isabel Sanford, American actress and comedianJack Sanford (1917-2005, first baseman), American baseball playerJack Sanford (1929-2000), American baseball playerJames Sanford (disambiguation), multiple peopleJohn A. Sanford (1929–2005), also known as Jack, American Jungian psychoanalyst and Episcopal priestJohn C. Sanford (born 1950), American plant geneticist and advocate of intelligent design and young earth creationismJohn E. Sanford (died 1907), U.S. politician in MassachusettsJohn Elroy Sanford, birth name of American comedian Redd FoxxJohn Langton Sanford (1824–1877), English historical writerJohn Sanford (author), American author and screenwriter, born Julian Lawrence ShapiroJohn Sanford (governor) (1605–1653), founder of Portsmouth, Rhode Island, USAJohn Sanford (1803) (1803–1857), U.S. Representative from New YorkJohn Sanford (1851) (1851–1939), U.S. Representative from New YorkJohn W. A. Sanford (1798–1870), United States Congressional Representative from the state of GeorgiaKatherine Sanford (1915-2005), American cancer biologistKiki Sanford, American neurophysiologist and science communicatorLeonard Cutler Sanford (1868–1950), American surgeon and ornithologistLillias Rumsey Sanford, American school founderLouis Childs Sanford, American Episcopal bishopLucius Sanford, American American football playerMaria L. Sanford, American educatorMark Sanford (1960– ), American South Carolina politicianMike Sanford, American college football coachMike Sanford Jr., American football coachMitchell Sanford (1799–1861), New York politicianNathan Sanford (1777–1838), New York politician, US SenatorNehemiah Curtis Sanford, American industrialist and politicianReuben Sanford (1780–1855), New York politicianRichard K. Sanford (1822–1895), New York politicianRoscoe Frank Sanford, American astronomerScott Sanford (born 1963), American politician, accountant, and Baptist clergymanT. Denny Sanford, American businessman and philanthropistTaylor Sanford, American baseball player, coach, and college athletics administratorTerry Sanford, American governor and senator from North CarolinaThomas Sanford, nuclear physicist at Sandia National Laboratories, awarded the Hannes Alfvén Prize in 2005William Eli Sanford, Canadian businessman, philanthropist, and politicianWinifred Sanford (1890 - 1983), American writer