Entrez 54843 | Ensembl ENSG00000137501 | |
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Aliases SYTL2, CHR11SYT, EXO4, PPP1R151, SGA72M, SLP2, SLP2A, synaptotagmin like 2 External IDs MGI: 1933366 HomoloGene: 131343 GeneCards: SYTL2 | ||
Function
The protein encoded by this gene is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. The SLP homology domain (SHD) of this protein has been shown to specifically bind the GTP-bound form of Ras-related protein Rab-27A (RAB27A), which suggests a role in vesicle trafficking. Multiple alternatively spiced transcript variants encoding distinct isoforms have been observed.
Interactions
SYTL2 has been shown to interact with RAB27A.
References
SYTL2 Wikipedia(Text) CC BY-SA