Species Human Entrez 6612 | Human Mouse Ensembl ENSG00000184900 | |
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Aliases SUMO3, SMT3A, SMT3H1, SUMO-3, Smt3B, small ubiquitin-like modifier 3 External IDs MGI: 1336201 HomoloGene: 38251 GeneCards: SUMO3 | ||
Small ubiquitin-related modifier 3 is a protein that in humans is encoded by the SUMO3 gene.
Contents
Function
SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 2002).[supplied by OMIM]
Interactions
SUMO3 has been shown to interact with ARNTL and Thymine-DNA glycosylase.
References
SUMO3 Wikipedia(Text) CC BY-SA