SSH3

Updated on Dec 27, 2024

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Species Human Entrez 54961		Human Mouse Ensembl ENSG00000172830

Aliases SSH3, SSH3L, slingshot protein phosphatase 3 External IDs MGI: 2683546 HomoloGene: 32372 GeneCards: SSH3

Protein phosphatase Slingshot homolog 3 is an enzyme that in humans is encoded by the SSH3 gene.

Function

The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002).[supplied by OMIM]

References

SSH3 Wikipedia

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