Entrez 30837 | Ensembl n/a | |
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Aliases SOCS7, NAP4, NCKAP4, suppressor of cytokine signaling 7 External IDs MGI: 2651588 HomoloGene: 16331 GeneCards: SOCS7 | ||
Suppressor of cytokine signaling 7 is a protein that in humans is encoded by the SOCS7 gene.
Contents
Model organisms
Model organisms have been used in the study of SOCS7 function. A conditional knockout mouse line, called Socs7tm1a(EUCOMM)Wtsi was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.
Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Twenty five tests were carried out on mutant mice and one significant abnormality was observed: homozygous mutant males showed a decreased response to stress-induced hyperthermia.
Interactions
SOCS7 has been shown to interact with NCK1.
References
SOCS7 Wikipedia(Text) CC BY-SA