Species Human Entrez 6601 | Human Mouse Ensembl ENSG00000139613 | |
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Aliases SMARCC2, BAF170, CRACC2, Rsc8, SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2 External IDs MGI: 1915344 HomoloGene: 2312 GeneCards: SMARCC2 | ||
SWI/SNF complex subunit SMARCC2 is a protein that in humans is encoded by the SMARCC2 gene.
Contents
Function
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. Two transcript variants encoding different isoforms have been found for this gene.
Interactions
SMARCC2 has been shown to interact with BAZ1B and SMARCA4.
References
SMARCC2 Wikipedia(Text) CC BY-SA