PubChem CID 24278699 ChEMBL CHEMBL520992 3D model (Jmol) Interactive image | ChemSpider 10131933 Formula C18H20ClNO2 Molar mass 317.81 g/mol | |
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SKF-83,959 is a synthetic benzazepine derivative used in scientific research which acts as an agonist at the D1-D2 dopamine receptor. It behaves as a full agonist at the D1 protomer and a high-affinity partial agonist at the D2 protomer. It was further shown to act as an allosteric modulator of the sigma-1 receptor. SKF-83,959 is a racemate that consists of the R-(+)- and S-(−)-enantiomers MCL 202 and MCL 201, respectively. SKF-83,959 inhibits sodium channels as well as delayed rectifier potassium channels.
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SKF-83,959 Wikipedia(Text) CC BY-SA