SkBr3 is a cell line isolated by the Memorial Sloan–Kettering Cancer Center in 1970. It was derived from a pleural effusion due to an adenocarcinoma originating in the breast of a 43-year-old, caucasian female. The cell line over-expresses the HER2 gene product.
The SkBr3 line is synonymous(derived from the same patient) with the AU565 cell line.
The SkBr3 cell line has been used in studies seeking to overcome Herceptin resistance to HER2-overexpressing breast cancer.
The cells are considered biosafety level 1.
References
SKBR3 Wikipedia(Text) CC BY-SA