Species Human Entrez 10572 | Human Mouse Ensembl ENSG00000184990 | |
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Aliases SIVA1, CD27BP, SIVA, Siva-1, Siva-2, SIVA1 apoptosis inducing factor External IDs MGI: 1353606 HomoloGene: 4692 GeneCards: SIVA1 | ||
Apoptosis regulatory protein Siva is a protein that in humans is encoded by the SIVA1 gene.
This gene encodes a protein with an important role in the apoptotic (programmed cell death) pathway induced by the CD27 antigen, a member of the tumor necrosis factor receptor (TFNR) superfamily. The CD27 antigen cytoplasmic tail binds to the N-terminus of this protein. Two alternatively spliced transcript variants encoding distinct proteins have been described.
Interactions
SIVA1 has been shown to interact with CD27.
References
SIVA1 Wikipedia(Text) CC BY-SA