Entrez 7979 | Ensembl ENSG00000127922 | |
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Aliases SEM1, DSS1, ECD, SHFD1, SHSF1, Shfdg1, SHFM1, split hand/foot malformation (ectrodactyly) type 1 External IDs MGI: 109238 HomoloGene: 38165 GeneCards: SEM1 | ||
26S proteasome complex subunit DSS1 is a protein that in humans is encoded by the SHFM1 gene.
Contents
Function
The product of this gene has been localized within the split hand/split foot malformation locus SHFM1 at chromosome 7. It has been proposed to be a candidate gene for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle.
Interactions
SHFM1 has been shown to interact with BRCA2.
References
SHFM1 Wikipedia(Text) CC BY-SA