Entrez 259230 | Ensembl ENSG00000198964 | |
Aliases SGMS1, MOB, MOB1, SMS1, TMEM23, hmob33, sphingomyelin synthase 1 External IDs MGI: 2444110 HomoloGene: 27040 GeneCards: SGMS1 | ||
Phosphatidylcholine:ceramide cholinephosphotransferase 1 is an enzyme that in humans is encoded by the SGMS1 gene.
Contents
Function
The protein encoded by this gene is predicted to be a five-pass transmembrane protein. This gene may be predominately expressed in brain.
Model organisms
Model organisms have been used in the study of SGMS1 function. A conditional knockout mouse line called Sgms1tm1a(EUCOMM)Wtsi was generated at the Wellcome Trust Sanger Institute. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping
References
SGMS1 Wikipedia(Text) CC BY-SA