Species Human Entrez 51639 | Human Mouse Ensembl ENSG00000115128 | |
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Aliases SF3B6, HSPC175, Ht006, P14, SAP14, SAP14a, SF3B14, SF3B14a, CGI-110, splicing factor 3b subunit 6 External IDs MGI: 1913305 HomoloGene: 9360 GeneCards: SF3B6 | ||
Splicing factor 3B, 14 kDa subunit, also known as SF3B14, is a human gene.
Contents
Function
This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.
Interactions
SF3B14 has been shown to interact with SF3B1.
References
SF3B14 Wikipedia(Text) CC BY-SA