Species Human Entrez 64218 | Human Mouse Ensembl ENSG00000196189 | |
Aliases SEMA4A, CORD10, RP35, SEMAB, SEMB, semaphorin 4A External IDs MGI: 107560 HomoloGene: 8425 GeneCards: SEMA4A | ||
Semaphorin-4A is a protein that in humans is encoded by the SEMA4A gene.
Contents
Function
SEMA4A is a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in guidance of axonal migration during neuronal development and in immune responses.[supplied by OMIM]
Clinical significance
A germline variant in SEMA4A (V78M) has been demonstrated to confer risk for colorectal cancer type X.
References
SEMA4A Wikipedia(Text) CC BY-SA