Species Human Entrez 6383 | Human Mouse Ensembl ENSG00000169439 | |
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Aliases SDC2, CD362, HSPG, HSPG1, SYND2, syndecan 2 External IDs MGI: 1349165 HomoloGene: 2253 GeneCards: SDC2 | ||
Syndecan-2 is a protein that in humans is encoded by the SDC2 gene.
Contents
Function
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types.
Interactions
SDC2 has been shown to interact with:
References
SDC2 Wikipedia(Text) CC BY-SA