Puneet Varma (Editor)

SCG2

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Species
  
Human

Entrez
  
7857

Human
  
Mouse

Ensembl
  
ENSG00000171951

Aliases
  
SCG2, CHGC, EM66, SN, SgII, secretogranin II

External IDs
  
MGI: 103033 HomoloGene: 2591 GeneCards: SCG2

SCG2, also called secretogranin II (chromogranin C), is a protein which in humans is encoded by the SCG2 gene.

Function

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.

References

SCG2 Wikipedia