Synonyms SB-612,111 PubChem CID 10047612 ChemSpider 8223175 Molar mass 418.398 g/mol | CAS Number 371980-98-2 IUPHAR/BPS 1693 ChEMBL CHEMBL559569 | |
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SB-612,111 is an opioid receptor ligand which is a potent and selective antagonist for the nociceptin receptor (ORL-1), several times more potent than the older drug J-113,397. It does not have analgesic effects in its own right, but prevents the development of hyperalgesia, and also shows antidepressant effects in animal studies.
References
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