Species Human Entrez 163786 | Human Mouse Ensembl ENSG00000156876 | |
Aliases SASS6, SAS-6, SAS6, MCPH14, SAS-6 centriolar assembly protein External IDs MGI: 1920026 HomoloGene: 45668 GeneCards: SASS6 | ||
Spindle assembly abnormal protein 6 homolog (SAS-6) is a protein that in humans is encoded by the SASS6 gene.
Contents
Function
SAS-6 is necessary for centrosome duplication and functions during procentriole formation; SAS-6 functions to ensure that each centriole seeds the formation of a single procentriole per cell cycle.
Clinical significance
Mutations in SASS6 are associated to MCPH .
References
SASS6 Wikipedia(Text) CC BY-SA