Rule is a surname. Notable people with the name include:
Albert Leroy Rule, World War I documentary film producer & director
Ann Rule (1935–2015), American true crime writer.
Bert L. Rule (1891–1878), Popular music composer & arranger
Bob Rule (born 1944), American basketball player
Christopher Rule (1895–1983), American comic book artist
Elton Rule (1916–90), American television executive
Francis Rule (born 1835), Cornish miner who moved to Mexico and became immensely wealthy.
Gilbert Rule (c. 1629–1701), Principal of Edinburgh University
Glenn Rule (born 1989), English soccer player
Ja Rule (born 1976), American rapper, singer and actor
Jack Rule, Jr. (born 1938), American professional golfer
Jane Rule (1931–2007), Canadian writer
Janice Rule (1931–2003), American actress
Margaret Rule (1928-2015), English underwater archaeologist
Stan Rule (1924-2007), Australian rules footballer
Stephen Rule (born 1952), English Rugby Union and Rugby League player and coach
Wendy Rule, Australian musical artist
William Rule (American editor) (1839–1928), American newspaper editor and politician
