Rothman is a surname. Notable people with the surname include:
Barbara Katz Rothman (born 1948), sociologistBenny Rothman (1911–2002), political activistDavid Rothman (statistician) (1935–2004), statisticianDavid Rothman, professor of medicineEinar Rothman (1888–1952), track and field athleteElise Rothman, fictional character from the television series CharmedGertjan Rothman (born 1983), footballerGöran Rothman (1739–1778), naturalist and physicianJames Rothman (born 1950), American cell biologist and 2013 Nobel Laureate in Physiology or MedicineJohn Rothman (born 1949), actorJudy Rothman, American screenwriter and lyricistKatherine RothmanKen Rothman (born 1935), American politician; Lieutenant Governor of MissouriLorraine Rothman (1932–2007), activistLouis Rothman (1869–1926), British tobacconist and founder of Rothmans InternationalMakua Rothman (born 1984), surferMark Rothman, writer and producer of Laverne and ShirleyMilton A. Rothman (1919–2001), nuclear physicistNorman Rothman (1914–1985), gangsterRichard B. Rothman, pharmacologistRodney Rothman, screenwriterSandy Rothman (born 1946), bluegrass musician and producerStephanie Rothman (born 1936), film directorSteve Rothman (born 1952), politicianThomas Rothman (born 1954), CEO of FOX Filmed EntertainmentTony Rothman (born 1953), physicist